Researchers identified SGK1 as a key chemical connecting childhood trauma to depression and suicidal behavior. High SGK1 levels were found in the brains of suicide victims and in people with genetic variants linked to early adversity. Drugs that block SGK1 could offer a new kind of antidepressant, especially for patients resistant to SSRIs.

A sweeping review of existing studies finds no solid evidence that using acetaminophen (Tylenol) during pregnancy increases the risk of autism or ADHD in children. Researchers found that previous reviews often relied on weak or biased data, and most did not properly account for genetic or environmental factors shared by families. When these factors were considered, any apparent link between acetaminophen use and neurodevelopmental disorders largely disappeared.